6 Common Household Chemicals that Don’t Play well Together

Often times people think that just because two products work that they will work even better if you combine them. I’m here to tell you today that that couldn’t be further from the truth. There are certain household products and chemicals that when mixed together create nothing but toxic chemical reactions. And even if it doesn’t produce a chemical reaction, you never know what type of effect it will have on the surface you plan to use it on. For your safety, and the safety of those around you, make sure you always read the product label and never mix the following products:

Acetaminophen & Alcohol

Two words, liver failure. Drinking alcohol activates enzymes. These enzymes can transform acetaminophen into chemicals that can cause liver failure. But just so we’re clear, you shouldn’t be mixing alcohol with anything. 

Ammonia & Bleach

When mixed together bleach and ammonia can create an extremely toxic gas called chloramine. Similar to mixing bleach and vinegar which we discuss below, this mixture can cause an array of health complications. You may experience shortness of breath and chest pains if exposed to the combination of ammonia and bleach.

Pro Tip : Never mix bleach with anything besides cold water.


There’s a reason batteries are sold in packs. Different brands of batteries contain different chemical compounds. If one of the batteries inside your device were to die and you switched it out for another one (different brand), the original battery could continue dispatching electricity into the device cause the batteries to leak. Boy was that a mouthful. If you have two different batteries inside a device that are leaking into it, you’re exposing that electronic device to potential damage.

Bleach & Vinegar 

Bleach and vinegar are probably the two strongest chemicals in your house. That may be the case when you use them separately. But mixing these two products can produce a toxic chlorine gas known to cause respiratory issues, burning, and watery eyes.

Ibuprofen & Alcohol 

Taking ibuprofen while consuming alcohol can cause stomach ulcers and tears in the stomach lining. Alcohol only
increases the risks. The only time you should be taking ibuprofen is on a full stomach with a glass of water.

Rubbing Alcohol & Bleach

Anyone who watches 20/20 probably knows what this mixture produces a little to well. Rubbing alcohol and bleached combined together creates chloroform. Although it takes a lot of each chemical to produce a deadly chloroform, the combination can still be toxic to the body causing respiratory problems and severe inflammation.

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